Spravato® (esketamine) has emerged as a promising treatment for adults with treatment-resistant depression (TRD) and major depressive disorder with suicidal thoughts. While the in-clinic experience is closely monitored, many patients are left wondering what to do after Spravato treatment once they’re back home.
What should recovery look like?
How can you maximize the benefits of each session? And what aftercare practices are most effective?
In this comprehensive guide from Excel Psychiatry, based in McKinney, Texas and led by board-certified psychiatrist Dr. Zainab Zia, we’ll walk you through everything you need to know about post-Spravato self care, recovery tips, and Spravato post treatment protocol protocols, you can feel safe, supported, and empowered on your healing journey.
The Importance of Aftercare Following Spravato
Spravato is administered through a nasal spray under the supervision of a healthcare professional.
Patients typically remain in the clinic for at least two hours following each session to monitor side effects like dizziness, disassociation, or increased blood pressure.
However, what happens after you leave the clinic plays a crucial role in your recovery.
Creating a Spravato aftercare plan helps your body and mind recover, improves treatment outcomes, and reduces discomfort from Spravato treatment side effects.
Aftercare requires awareness, self-compassion, and clear communication with your mental health provider.
Immediate Steps: What to Do Right After Spravato Treatment
1. Prioritize Rest
One of the most common Spravato rest recommendations is to give your body adequate time to recover. You may feel groggy, emotionally sensitive, or mentally foggy, this is entirely normal. Avoid any activity that requires alertness, such as driving or operating machinery.
How long should I rest after a Spravato session?
While individual responses vary, we recommend planning for at least the remainder of the day off, ideally with no major obligations.
2. Don’t Drive
Due to the dissociative effects of esketamine, patients are advised not to drive for the rest of the day. Always arrange for a trusted friend or family member to drive you home.
3. Stay Hydrated and Nourished
Your body may feel depleted, so drink plenty of water and have light, nutritious meals. Avoid heavy or greasy foods that might upset your stomach.
4. Create a Calm Environment
Once you’re home, settle into a quiet space. Dimming the lights, playing soothing music, or journaling your experience can help bring emotional clarity. Your brain is still processing, let it do so gently.
Spravato Recovery Process: Days Following Treatment
1. Monitor Side Effects
While most side effects are mild and temporary, you should keep track of any symptoms like:
- Nausea
- Dizziness
- Headaches
- Anxiety
- Fatigue
- Dissociation
Your provider at Excel Psychiatry will monitor these over time. You’ll likely experience fewer side effects as your body adjusts to the medication.
2. Journal and Track Mood
One of the most helpful Spravato mood tracking after treatment strategies is daily journaling. This allows you to observe patterns in emotions, energy levels, and mental clarity, which can guide your provider in adjusting your treatment plan.
How do I best support mood and symptoms tracking after treatment?
Use a mood-tracking app, or keep a daily log of your feelings, sleep quality, and overall energy. Share it with your provider during follow-ups.
3. Stay in Touch With Your Provider
Spravato follow-up care is essential. Regular check-ins with your psychiatrist ensure the treatment remains on track and effective. At Excel Psychiatry, we personalize follow-up plans based on your progress and evolving needs.
Self-Care Guidelines After Spravato
1. Avoid Alcohol and Cannabis
Both alcohol and cannabis can interact negatively with Spravato. These substances may worsen depression symptoms or increase side effects like dizziness, disorientation, or mood instability.
Should I avoid alcohol or cannabis after Spravato?
Absolutely. For your safety and optimal treatment results, steer clear of both, especially in the first 48–72 hours post-treatment.
2. Maintain Sleep Hygiene
Spravato can impact your sleep in either direction, some people feel very sleepy, while others report a spike in alertness. Either way, prioritize a consistent sleep schedule, low screen time before bed, and a cool, quiet sleeping space.
3. Engage in Gentle Movement
Light movement like walking, stretching, or yoga can help you reconnect with your body after a session. Avoid high-intensity workouts or physically demanding tasks for at least 24 hours.
4. Lean on Your Support System
Open up to a trusted friend, therapist, or family member about your experiences. Having emotional support during your treatment course can ease the psychological burden and boost your recovery confidence.
How Long Do the Effects of Spravato Last?
Initial benefits may be felt within hours or days, but long-term relief generally builds over multiple sessions. Some people notice an emotional “dip” a day or two after their session, while others feel progressively lighter.
It’s important not to judge your entire treatment plan by just one or two sessions. With time and consistency, most patients report profound improvements in mood, function, and quality of life.
Setting Expectations: It’s a Journey, Not a Quick Fix
While Spravato can be highly effective, it’s not a magic wand. The Spravato recovery process involves continuous collaboration between you and your mental health provider.
Excel Psychiatry’s approach is to work with you long-term, integrating Spravato into a broader treatment framework that may include therapy, lifestyle changes, and medication management.
Final Thoughts: Building a Healthy Routine
Every Spravato session is an opportunity, not just for symptom relief, but for personal transformation. With proper Spravato post treatment protocol, you’re not just recovering, you’re rebuilding.
The key is to remain patient, consistent, and open with your care team. At Excel Psychiatry, we’re here to walk this path with you.
Frequently Asked Questions (FAQs)
1. How long should I rest after a Spravato session?
Plan for a full day of rest. Avoid driving, working, or making any major decisions.
2. When can I drive or return to work post‑Spravato?
You should not drive until the next day. Most people return to work within 24 hours, depending on how they feel.
3. What common side effects should I monitor afterwards?
Dizziness, nausea, fatigue, dissociation, and headaches are common but temporary. Contact your provider if they persist or worsen.
4. How do I best support mood and symptoms tracking after treatment?
Use a mood journal or app to log emotional changes, energy levels, and sleep. Share with your provider for personalized care.
5. Should I avoid alcohol or cannabis after Spravato?
Yes. Both can interfere with treatment and may worsen side effects. Avoid for at least 72 hours post-treatment.
Medical Disclaimer:
This blog is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult with your psychiatrist or healthcare provider regarding any questions or concerns about your treatment plan.
