Spravato Treatment for Depression
What Is Spravato Treatment?
Spravato® is an FDA-approved nasal spray for depression, used alongside an oral antidepressant to treat:
- Treatment-resistant depression (TRD) in adults
- Major depressive disorder (MDD) with acute suicidal thoughts or behaviors
This therapy involves ketamine nasal spray therapy, specifically esketamine, which works on NMDA receptors in the brain, a mechanism different from traditional antidepressants. If you’re researching “what is Spravato treatment” or “how does Spravato work for depression,” you’re not alone. It’s designed to rapidly reduce symptoms where oral medications have failed.
At Excel Psychiatry, we are a certified Spravato treatment center in McKinney, TX, offering innovative care for patients struggling with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal ideation. If traditional antidepressants haven’t worked for you, Spravato® (esketamine) may offer a new path forward.
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How Does Spravato Work?
Spravato is believed to rebalance glutamate, a neurotransmitter critical to mood and cognition, by targeting NMDA receptors. While the exact mechanism is not fully understood, clinical studies show significant improvement in depressive symptoms, often within hours or days of the first treatment. For many, this alternative to antidepressants is a life-changing solution.
What to Expect During Spravato Treatment
As a trusted Spravato treatment center, our process is designed for comfort and safety:
In-Office Only
Spravato is not a take-home treatment. It must be administered in a certified medical setting.
Comfortable Setting
You’ll relax in a private or semi-private recliner room at our McKinney clinic.
Guided Self-Administration
A provider will instruct you on using the nasal spray for depression.
Monitoring Period
You’ll be supervised for 2 hours for safety and support.
Transportation Required
Due to possible side effects, patients must arrange for a ride home.
Spravato Treatment Side Effects
Like all medications, Spravato may cause side effects. The most common include:
- Dissociation
- Dizziness
- Sedation or lethargy
- Increased blood pressure
- Vertigo
- Hypoesthesia (numbness or tingling)
Patients receiving Spravato for treatment-resistant depression or MDD with suicidal ideation are closely monitored in our clinic to manage these effects.
Frequently Asked Questions
What is Spravato treatment?
Spravato is a prescription nasal spray for depression, FDA-approved for adults with treatment-resistant depression and MDD with suicidal thoughts. It must be used alongside an oral antidepressant.
What are the side effects of TMS treatment?
Some patients notice symptom relief after the first few treatments. Significant improvements are often observed within 2–4 weeks.
How long does Spravato take to work?
Common side effects include dizziness, dissociation, increased blood pressure, and nausea. Patients are monitored in-clinic for 2 hours post-treatment.
What are the side effects of Spravato?
Most patients begin with twice-weekly sessions for 4 weeks, then transition to once-weekly or biweekly sessions as advised by their provider.
How long is the Spravato treatment?
Most patients begin with twice-weekly sessions for 4 weeks, then transition to once-weekly or biweekly sessions as advised by their provider.
How many Spravato treatments are needed?
The number of treatments depends on your diagnosis and response to therapy. Your psychiatrist will tailor a plan that best supports your recovery.
What to do during Spravato treatment?
Sit back, relax, and allow your mind and body to process the treatment. Our care team is nearby for support throughout your visit.
Ready to Take the Next Step?
If you’re struggling with treatment-resistant depression or suicidal symptoms, don’t wait. Spravato treatment offers a proven, fast-acting alternative to traditional antidepressants. Let Excel Psychiatry help you reclaim control of your life.
